Vioxx ® (Rofecoxib)		Vioxx pricing
	Brand Vioxx manufactured by: MERCK
	Chemical name: Rofecoxib (Generic not available)

Anti-inflammatory--Analgesic Agent

Vioxx Information | How to take Vioxx | Vioxx Side Effects

Vioxx Common Use: Vioxx reduces the joint swelling, redness and pain of arthritis.

IMPORTANT NOTE: The following information is intended to heighten awareness of health information and does not suggest diagnosis or treatment. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

What is Vioxx? Vioxx is a nonsteroidal anti-inflammatory drug (NSAID) which reduces the joint swelling, redness and pain of arthritis. Your body produces chemicals called prostaglandins. Some of these prostaglandins help line the stomach with a protective layer. In arthritis, other prostaglandins cause pain and swelling. Vioxx reduces the type that causes pain and swelling. At prescribed doses, Vioxx does not affect the type that maintains the protective layer of the stomach, and reduces the chances of bleeding.

This medicine does not cure arthritis, but promotes suppression of the inflammation and tissue damaging effects resulting from this inflammation. Vioxx will help you only as long as you continue to take it.

Vioxx is available as a tablet or an oral liquid.

Why has my doctor prescribed Vioxx? Your doctor has prescribed Vioxx for:

• treatment of osteoarthritis
• relief of pain
• treatment of menstrual pain

What is osteoarthritis? Osteoarthritis is a joint disease. It results from the gradual breakdown of the cartilage that cushions the ends of bones, resulting in pain, inflammation, tenderness, stiffness, and physical disability.

What else can I do to help manage my osteoarthritic pain? Talk to your doctor about:

• Exercise
• Controlling your weight
• Hot and cold treatments
• Using support devices

Before Taking This Medication Tell Your Doctor and Pharmacist if You:

• or a family member are allergic to or have had a reaction to the active or inactive ingredients contained in Vioxx, or to other anti-inflammatory drugs (such as acetylsalicylic acid [ASA], diclofenac, diflunisal, fenoprofen, flurbiprofen, ibuprofen, indomethacin, ketoprofen, mefenamic acid, naproxen, piroxicam, sulindac, tiaprofenic acid, tolmetin, nabumetone or tenoxicam) manifesting itself by increased sinusitis, hives, the initiating or worsening of asthma or anaphylaxis (sudden collapse);
• or a family member have had asthma, nasal polyps, chronic sinusitis or chronic urticaria (hives);
• have a history of stomach upset, ulcers, liver or kidney diseases;
• have blood or urine abnormalities;
• have a history of angina, heart attack or a blocked artery in your heart;
• have high blood pressure or heart failure;
• have fluid retention like swelling of the legs;
• have diabetes;
• are on any special diet, such as a low-sodium or low-sugar diet;
• are pregnant or intend to become pregnant while taking this medication;
• are breast-feeding or intend to breast-feed while taking this medication;
• are taking any other medication (either prescription or nonprescription) such as NSAIDs, theophylline (a medicine used to treat asthma), warfarin (a blood thinner), rifampin (an antibiotic), angiotensin converting enzyme (ACE) inhibitors (medicines used for high blood pressure and heart failure), or lithium (a medicine used to treat a certain type of depression).

While Taking This Medication:

• tell any other doctor, dentist or pharmacist that you consult or see, that you are taking this medication;
• some NSAIDs may cause drowsiness or fatigue in some people taking them. Do not drive or participate in activities that require alertness if you are drowsy, dizzy or lightheaded after taking this medication;
• check with your doctor if you are not getting any relief of your arthritis or if any problems develop;
• report any untoward reactions to your doctor. This is very important as it will aid in the early detection and prevention of potential complications;
• stomach problems may be more likely to occur if you drink alcoholic beverages. Therefore, do not drink alcoholic beverages while taking this medication;
• check with your doctor immediately if you experience unexpected weakness while taking this medication, or if you vomit any blood or have dark or bloody stools;
• some people may become more sensitive to sunlight than they are normally. Exposure to sunlight or sunlamps, even for brief periods of time, may cause sunburn, blisters on the skin, skin rash, redness, itching or discoloration, or vision changes. If you have a reaction from the sun, check with your doctor;
• check with your doctor immediately if chills, fever, muscle aches or pains, or other flu-like symptoms occur, especially if they occur shortly before or together with a skin rash. Very rarely, these effects may be the first signs of a serious reaction to this medication;
• your regular medical checkups are essential.

Side Effects of This Medication: Along with its beneficial effects, Vioxx may occasionally cause some undesirable reactions, especially when used for a long time or in large doses.

Elderly, frail or debilitated patients often seem to experience more frequent or more severe side effects. Although these side effects are not common, when they do occur they may require medical attention.

Check With Your Doctor Immediately if Any of the Following Are Noted:

• serious stomach problems such as ulcer or bleeding symptoms (for instance, stomach burning or black tarry stools, which are signs of possible stomach bleeding);
• shortness of breath, wheezing, any trouble in breathing or tightness in the chest;
• chest pain;
• allergic reactions including swelling of the face, lips, tongue, and/or throat which may cause difficulty in breathing or swallowing; hives, rash, and itching;
• vomiting or persistent indigestion, nausea, stomach pain or diarrhea;
• yellow discoloration of the skin or eyes;
• any change in the amount of or colour of your urine (dark red or brown);
• any pain or difficulty experienced while urinating;
• swelling of the feet or lower legs;
• unexplained weight gain;
• malaise, fatigue, drowsiness, loss of appetite;
• blurred vision or any visual disturbance;
• anxiety, mental confusion, difficulty concentrating, depression, dizziness, lightheadedness, hallucinations, tingling sensation, headache, vertigo (false sensation of movement or spinning);
• unusual headache with stiff neck (aseptic meningitis);
• hearing problems;
• hair loss, severe skin reaction.

Heart attacks and similar serious events have been reported in patients taking Vioxx.

Additionally, the following have been reported: heart failure; serious kidney problems, increased levels of potassium in the blood, decreased levels of sodium in the blood, fluid in the lungs, low blood cell counts, palpitations, pancreatitis, serious liver problems.

Other side effects not listed above may also occur in some patients. If you notice any other effects that you may consider important, check with your doctor or pharmacist without delay.

How should I take Vioxx? Vioxx should be taken once a day.

Your doctor will decide what dose of Vioxx you should take and how long you should take it.

For treatment of osteoarthritis:

• The recommended starting dose is 12.5 mg once a day.
• Your doctor may increase the dose to 25 mg once a day.
• The maximum recommended dose is 25 mg once a day.

For the relief of acute pain and the treatment of menstrual pain:

• On the first day, the recommended initial dose is 50 mg once a day.
• On the second day and after that, the dose should be 25 or 50 mg once a day as prescribed by your doctor.
• The maximum recommended dose is 50 mg once a day.
• Vioxx was studied in the management of acute pain for up to 5 days.

Vioxx can be taken with low-dose ASA (less than or equal to 325 mg daily) when indicated by a doctor. If you are currently taking low-dose ASA for prevention of heart attack or stroke, you should not discontinue without consulting your doctor because Vioxx is not a substitute for ASA for prevention of heart attack or stroke.

You may take Vioxx with or without food.

What should I do if I miss a dose? Try to take Vioxx as prescribed. However, if you miss a dose, do not take an extra dose. Just resume your usual schedule the following day.

What should I do in case of an overdose? If you take more than the prescribed dosage, contact your doctor immediately.

How should I store Vioxx tablets? Store at room temperature (15 to 30°C).

Oral Suspension: Store at room temperature (15 to 30°C). Protect from freezing. Shake well before using.

Vioxx is not recommended for patients under 18 years of age since safety and effectiveness have not been established.

Do not take Vioxx during pregnancy unless specifically prescribed by a doctor.

Do not keep outdated medicine or medicine no longer needed.

Keep out of the reach of children.

This medicine has been prescribed for your medical problem. Do not give it to anyone else.

Vioxx tablets contain the following inactive ingredients: croscarmellose sodium, hydroxypropylcellulose, lactose, magnesium stearate, microcrystalline cellulose and yellow ferric oxide.

Vioxx oral suspension contains the following inactive ingredients: citric acid (monohydrate), purified water, sodium citrate (dihydrate), sorbitol solution, strawberry flavor, and xanthan gum. Added as preservatives are sodium methylparaben 0.13% and sodium propylparaben 0.02%.

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